Peptide Database

Peptide NameLH alpha 1-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC449H704N124O134S14

DescriptionStandard

        GEFTMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNVRVENHTECHCSTCYYHKS
    

Molecular Weight10432.05 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)5.93

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0637

GRAVY Index-0.46

Hydrophobic Moment 0.62

Boman Index-0.07

Instability Index52.83

Aliphatic Index 39.89

Aromaticity 0.0968

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4143.96

LogP -46.76

H-bond Donors 153.0

H-bond Acceptors 157.0

Rotatable Bonds 339.0

Heavy Atoms 721.0

Ring Count 18.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035768 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyLH alpha

Tax ID9940

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide8-32; 11-61; 29-83; 33-85; 60-88

Other Mods53:N-linked (GlcNAc...) asparagine; 79:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour