MYP_110665
Basic Information
Entry 26
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antiviral
Antiviral Anti-Flavivirus Anti-Dengue virus
Antiviral Antiviral mechanism Viral replication inhibition
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
8 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RRRKSXSF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide with noncanonical residue [Cyclic]
mixed L/D amino-acid peptide (D-Arg1, Phe8) [Mixed]
not reported
not reported
The 'X' at position 6 indicates biphenylalanine (L-bPhe). The N-terminal and C-terminal cyclized by a amide bond
Bio-Activity Profile
Antimicrobial Antiviral
dengue virus 2(DENV2):inhibition of the activity of NS2B-NS3 protease
3.7 μM
IC50
RECORD: Rec_0404100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide with noncanonical residue [Cyclic]
mixed L/D amino-acid peptide (D-Arg1, Phe8) [Mixed]
not reported
not reported
The 'X' at position 6 indicates biphenylalanine (L-bPhe). The N-terminal and C-terminal cyclized by a amide bond
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
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