Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC113H177N27O44

DescriptionStandard

        QPELAPEDPEDSALLEDPVGTVAPQ
    

Molecular Weight2617.77 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.23

Net Charge (pH 7.4) -7.44

Charge Density (pH 7.0) -0.2890

GRAVY Index-0.65

Hydrophobic Moment 0.34

Boman Index0.03

Instability Index93.00

Aliphatic Index 82.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1105.51

LogP -11.51

H-bond Donors 32.0

H-bond Acceptors 37.0

Rotatable Bonds 78.0

Heavy Atoms 184.0

Ring Count 5.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161464 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0423813 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyVirus-derived peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); J-nectin 1

MethodLacZ assay

PaperA heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion. | Gianni T, Menotti L, Campadelli-Fiume G. | J Virol. 2005 | PMID:15890943 PMID15890943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15890943/