Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC543H875N147O159S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSAFISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTTSISLASCRTTSGIIDIKLNGKN
    

Molecular Weight12102.84 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0376

GRAVY Index0.15

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index19.50

Aliphatic Index 102.68

Aromaticity 0.0714

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4891.76

LogP -51.68

H-bond Donors 174.0

H-bond Acceptors 169.0

Rotatable Bonds 401.0

Heavy Atoms 852.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007443 VERIFIED: NO

Provenance & Taxonomy

OrganismErpornis zantholeuca [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria