Peptide Database

Peptide Namebeta-Atrial patriuretic peptide [16-48]

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC150H245N53O44S2

DescriptionStandard

        LAGPRSLRRSSCFGGRIDRIGAQSGLGCNSFRY
    

Molecular Weight3559.01 Da

Isoelectric Point (pI)11.33

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.1436

GRAVY Index-0.37

Hydrophobic Moment 0.64

Boman Index-0.16

Instability Index82.86

Aliphatic Index 65.15

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1601.99

LogP -22.07

H-bond Donors 62.0

H-bond Acceptors 51.0

Rotatable Bonds 118.0

Heavy Atoms 249.0

Ring Count 4.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028705 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0347127 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyAuriculin

Tax ID10116

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide12-28

Other Mods11:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation ACE inhibitory

Targetadipose tissue

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0409362 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyAuriculin

Tax ID10116

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide12-28

Other Mods11:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation ACE inhibitory

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min