Peptide Database

Peptide NameCecropin-B type 1 (Cecropin-B1) [Cleaved into: Cecropin-B (AalCecB); Cecropin-B amidated isoform]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC297H504N76O75S

DescriptionStandard

        MNFNKLFALVLLIGLVLLTGQTEAGGLKKLGKKLEGVGKRVFKASEKALPVLTGYKAIGK
    

Molecular Weight6371.71 Da

Isoelectric Point (pI)10.24

Net Charge (pH 7.0)7.50

Net Charge (pH 7.4) 7.26

Charge Density (pH 7.0) 0.1250

GRAVY Index0.35

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index13.54

Aliphatic Index 123.50

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2435.85

LogP -16.06

H-bond Donors 84.0

H-bond Acceptors 84.0

Rotatable Bonds 226.0

Heavy Atoms 449.0

Ring Count 5.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219087 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes albopictus [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria