‹ ›
MYP_110592
← PREVIOUS NEXT → BACK
Basic Information
Bass hepcidin (fish, chordates, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C86H135N29O25S9
Standard
Sequence
GCRFCCNCCPNMSGCGVCCRF
Physicochemical Analysis
2263.76 Da
8.23
1.68
1.36
0.0800
0.58
0.42
0.06
38.25
13.81
0.0952
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
866.74
-12.90
38.0
36.0
69.0
149.0
3.0
22.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0217043 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Shigella flexneri ATCC 12022
22 μM
MIC
PMID11985602;15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11985602/
RECORD: Rec_0218523 VERIFIED: NO
Provenance & Taxonomy
White bass [Animal]; Actinopterygii [Animal]
Hepcidin
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID10931184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10931184/
RECORD: Rec_0221418 VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]; Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
2-8; 5-19; 6-18; 9-15
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
RECORD: Rec_0239597 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Toxic Hemolytic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0307063 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Klebsiella pneumoniae ATCC 10031
22 μM
MIC
PMID11985602;15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11985602/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records · Page 3 of 4