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MYP_110592
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Basic Information
Bass hepcidin (fish, chordates, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C86H135N29O25S9
Standard
Sequence
GCRFCCNCCPNMSGCGVCCRF
Physicochemical Analysis
2263.76 Da
8.23
1.68
1.36
0.0800
0.58
0.42
0.06
38.25
13.81
0.0952
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
866.74
-12.90
38.0
36.0
69.0
149.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081592 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops x Morone saxatilis [Animal]
Hepcidin
45352
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
2-19; 5-8; 6-15; 9-18
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Immunomodulatory ACE inhibitory
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Hepcidin (Morone chrysops x Morone saxatilis): PMID 15546886 PMID15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15546886/
RECORD: Rec_0111961 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Escherichia coli ATCC D31K
11 μM
MIC
PMID11985602;15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11985602/
RECORD: Rec_0148555 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Aspergillus niger
44 μM
MIC
PMID11985602;15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11985602/
RECORD: Rec_0202515 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Rat erythrocytes
100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15546886/ PMID15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15546886/
RECORD: Rec_0202815 VERIFIED: YES
Provenance & Taxonomy
Morone chrysops [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
enterocolitica ATCC 23
PMID11985602;15546886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11985602/
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