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MYP_110553
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Basic Information
Brevinin-1AN1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C111H194N26O28S2
Standard
Sequence
FLTGVLKLASKIPSVLCAVLKTC
Physicochemical Analysis
2405.02 Da
9.39
2.74
2.50
0.1190
1.34
0.58
0.37
-1.77
148.26
0.0435
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
853.71
-5.28
32.0
33.0
79.0
167.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034425 VERIFIED: YES
Provenance & Taxonomy
Babina adenopleura [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 981
19 μM
MIC
PMID25001915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25001915/
RECORD: Rec_0038460 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0071864 VERIFIED: YES
Provenance & Taxonomy
Babina adenopleura [Animal]
Pleurain
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
17-23
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/E1B2T8/entry
RECORD: Rec_0085220 VERIFIED: YES
Provenance & Taxonomy
Olive frog [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
17-23
Bio-Activity Profile
Antimicrobial
PMID18494941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18494941/
RECORD: Rec_0093226 VERIFIED: YES
Provenance & Taxonomy
Babina adenopleura [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus carnosus KHS
37.5 μM
MIC
PMID25001915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25001915/
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