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MYP_110552
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Basic Information
Neocryptolepine 9(GG)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C4H8N2O3
Standard
Sequence
GG
Physicochemical Analysis
132.12 Da
5.53
-0.24
-0.44
-0.1200
-0.40
0.31
0.48
66.70
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
-1.85
3.0
3.0
3.0
9.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0409793 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnimal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation
RECORD: Rec_0416876 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans SN250
500 μg/mL
MIC
PMID24686017;22574992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24686017/
RECORD: Rec_0418042 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
PMID24686017;22574992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24686017/
RECORD: Rec_0426659 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse fibroblasts BALB/3T3 (IC50 at 2.11+-0.20 microM, Mouse fibroblasts BALB/3T3 (IC50 at 1.71+-0.34 microM, Human erythrocytes (10% Hemolysis at 300 microM
3 μM
Hemolysis
PMID24686017;22574992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24686017/
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