Peptide Database

Peptide NameBrevinin-1JDc

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC123H208N30O27S2

DescriptionStandard

        FLPAVLRVAAKVVPTVFCLISKKC
    

Molecular Weight2603.28 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1557

GRAVY Index1.33

Hydrophobic Moment 0.63

Boman Index0.32

Instability Index46.17

Aliphatic Index 137.92

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 895.46

LogP -3.55

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 82.0

Heavy Atoms 182.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414774 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana jingdongensis [Animal]

FamilyBrevinin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide18-24

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus (MRSA)

Activity8 μg/mL

MethodMIC

RECORD: Rec_0420851 VERIFIED: YES