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MYP_110538
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
10 amino acids
C52H99N19O13
Standard
Sequence
ASLRVRIKKQ
Physicochemical Analysis
1198.46 Da
12.00
3.79
3.60
0.3794
-0.68
0.15
-0.49
43.41
117.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
564.38
-5.43
21.0
17.0
44.0
84.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096187 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0144418 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Human cytomegalovirus (Virus entry); UL54 2F7
90 %
EGFP expression
PaperPeptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate. | Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G. | Antiviral Res. 2010 | PMID:20083141 PMID20083141 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20083141/
RECORD: Rec_0194618 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 20.0%, C 80.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0306947 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 1 (Replication); Vero
0.21 μM
EC50
PaperReduced HIV transmission at subsequent pregnancy in a resource-poor setting. | Gumbo FZ, Kandawasvika GQ, Duri K, Mapingure MP, Kurewa NE, Nathoo K, Rusakaniko S, Chirenje MZ, Stray-Pedersen B. | Trop Doct. 2011 | PMID:21576348 PMID21576348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21576348/
RECORD: Rec_0309774 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 2 (Replication); Vero
0.78 μM
EC50
PaperReduced HIV transmission at subsequent pregnancy in a resource-poor setting. | Gumbo FZ, Kandawasvika GQ, Duri K, Mapingure MP, Kurewa NE, Nathoo K, Rusakaniko S, Chirenje MZ, Stray-Pedersen B. | Trop Doct. 2011 | PMID:21576348 PMID21576348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21576348/