Peptide Database

Peptide NameAngiotensin I

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC61H87N17O14

DescriptionStandard

        DRVYVHPFHL
    

Molecular Weight1282.45 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0065

GRAVY Index-0.23

Hydrophobic Moment 0.36

Boman Index0.06

Instability Index10.30

Aliphatic Index 97.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 493.22

LogP -1.51

H-bond Donors 17.0

H-bond Acceptors 16.0

Rotatable Bonds 36.0

Heavy Atoms 92.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143920 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]; Canis familiaris [Animal]; Cavia porcellus [Animal]; Oryctolagus cuniculus [Animal]; Trachemys scripta,Pseudemys scripta [Animal]; Ambystoma mexicanum [Animal]

FamilyAngiotensin

Tax ID9913, 9615, 10141, 9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0244697 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familyserpin family

Tax ID9913; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone serpin family

RECORD: Rec_0249188 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyAngiotensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour