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MYP_110468
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Basic Information
R3 (Bac2A variant through single amino acid substitution)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C66H127N27O13
Standard
Sequence
RLRRIVVIRVAR
Physicochemical Analysis
1506.89 Da
12.00
4.76
4.56
0.3967
0.39
0.21
-0.41
65.88
178.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
692.92
-4.83
28.0
18.0
52.0
106.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008678 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
16 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0040391 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US20080207522A1/en PatentUS 2008/0207522 A1
RECORD: Rec_0053841 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
8 μg/mL
MIC
PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0059294 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC25923
16 μM
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0096230 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
8 μg/mL
MIC
PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
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