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MYP_110428
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Basic Information
Natriuretic peptide TNP-b
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C157H257N49O48S2
Standard
Sequence
SDPKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKK
Physicochemical Analysis
3663.15 Da
8.84
1.53
1.23
0.0437
-0.56
0.44
-0.07
41.85
72.29
0.0286
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1549.96
-19.36
53.0
53.0
119.0
256.0
6.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094949 VERIFIED: YES
Provenance & Taxonomy
Oxyuranus scutellatus canni [Animal]
Natriuretic peptide TNP
183720
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Natriuretic peptide TNP-b (Oxyuranus scutellatus canni): PMID 15652496 PMID15652496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15652496/
RECORD: Rec_0120114 VERIFIED: YES
Provenance & Taxonomy
Oxyuranus microlepidotus [Animal]
Natriuretic peptide TNP
111177
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Natriuretic peptide TNP-b (Oxyuranus microlepidotus): PMID 15652496 PMID15652496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15652496/
RECORD: Rec_0259433 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 5.7%, T 37.1%, C 57.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0415454 VERIFIED: NO
Provenance & Taxonomy
Oxyuranus microlepidotus [Animal]; Oxyuranus scutellatus scutellatus [Animal]; Oxyuranus scutellatus canni [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-25
Bio-Activity Profile
Neuropeptide