Peptide Database

Peptide Namehuman LL-29

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC160H262N48O38

DescriptionStandard

        LGNFFRKARKKIGEEFKRIVQRIKDFLQ
    

Molecular Weight3466.09 Da

Isoelectric Point (pI)11.05

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.2058

GRAVY Index-0.75

Hydrophobic Moment 0.89

Boman Index-0.31

Instability Index16.32

Aliphatic Index 83.57

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1467.89

LogP -10.06

H-bond Donors 52.0

H-bond Acceptors 44.0

Rotatable Bonds 126.0

Heavy Atoms 246.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244071 VERIFIED: YES

Provenance & Taxonomy

OrganismHylobates moloch [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)