Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC458H723N123O142S11

DescriptionStandard

        MPLSMIICTKRFEKLYSEIHNSSTISEKAEYSTKENKAARIKEHYDVFDPWKACIKLNGQCKNQCGENEFKMSYCARPETLCCLKECDPVE
    

Molecular Weight10577.09 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.86

Charge Density (pH 7.0) -0.0042

GRAVY Index-0.66

Hydrophobic Moment 0.65

Boman Index-0.14

Instability Index61.71

Aliphatic Index 59.01

Aromaticity 0.0879

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4319.51

LogP -42.37

H-bond Donors 155.0

H-bond Acceptors 155.0

Rotatable Bonds 360.0

Heavy Atoms 734.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212933 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx canadensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal