Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length140 amino acids

Chemical FormulaC691H1086N184O184S15

DescriptionStandard

        MVWLISSPQSWLRSSCILGTTGPLTPPWASCCPRSCLDLQPNKGWAPSSRAQLAWFLFSCVLPSSPSPDLVAMTQLLLLIVALLVLGHVPPGRSEFKRCWKGQGACRPYCTRHEAYMQLCPDASLCCLAYGLKMAKIENV
    

Molecular Weight15396.11 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)5.57

Net Charge (pH 7.4) 5.07

Charge Density (pH 7.0) 0.0398

GRAVY Index0.24

Hydrophobic Moment 0.55

Boman Index0.16

Instability Index87.55

Aliphatic Index 92.00

Aromaticity 0.0857

Extinction Coeff. Reduced 37470.00

Extinction Coeff. Oxidized 38095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5734.47

LogP -49.39

H-bond Donors 209.0

H-bond Acceptors 207.0

Rotatable Bonds 478.0

Heavy Atoms 1074.0

Ring Count 34.0

Amide Bonds 147.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248357 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0379172 VERIFIED: NO