Peptide Database

Peptide NameInterferon regulatory factor 3

Function Ontology

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Immunology ▸ Immunomodulation ▸ Innate immune transcription factor

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length427 amino acids

Chemical FormulaC2112H3242N582O626S13

DescriptionStandard

        MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES
    

Molecular Weight47218.70 Da

Isoelectric Point (pI)5.17

Net Charge (pH 7.0)-13.69

Net Charge (pH 7.4) -14.55

Charge Density (pH 7.0) -0.0321

GRAVY Index-0.45

Hydrophobic Moment 0.71

Boman Index0.01

Instability Index46.75

Aliphatic Index 76.44

Aromaticity 0.0867

Extinction Coeff. Reduced 88920.00

Extinction Coeff. Oxidized 89295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351312 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIRF

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Anti-SARS-CoV-2 Innate immune transcription factor

TargetSARS-CoV-2