Peptide Database

Peptide NameFa-AMP1 (Fagopyrum antimicrobial peptide 1; hevein-type; Plant defensin)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC156H237N49O52S8

DescriptionStandard

        AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCK
    

Molecular Weight3887.37 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0428

GRAVY Index-0.21

Hydrophobic Moment 0.23

Boman Index0.12

Instability Index29.25

Aliphatic Index 19.75

Aromaticity 0.0750

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1601.09

LogP -26.47

H-bond Donors 62.0

H-bond Acceptors 62.0

Rotatable Bonds 120.0

Heavy Atoms 265.0

Ring Count 7.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346404 VERIFIED: YES

Provenance & Taxonomy

OrganismFagopyrum esculentum [Plant]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetFusarium oxysporum

RECORD: Rec_0358653 VERIFIED: YES

Provenance & Taxonomy

OrganismFagopyrum esculentum [Plant]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetAgrobacterium rhizogenes

RECORD: Rec_0378633 VERIFIED: YES

Provenance & Taxonomy

OrganismFagopyrum esculentum [Plant]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetGeotrichum candidum

RECORD: Rec_0391876 VERIFIED: YES

Provenance & Taxonomy

OrganismFagopyrum esculentum [Plant]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetClavibacter michiganensis

Activity14 μg/mL

MethodIC50

RECORD: Rec_0393243 VERIFIED: YES

Provenance & Taxonomy

OrganismFagopyrum esculentum [Plant]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetAgrobacterium radiobacter

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