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MYP_110313
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Basic Information
Fa-AMP1 (Fagopyrum antimicrobial peptide 1; hevein-type; Plant defensin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
40 amino acids
C156H237N49O52S8
Standard
Sequence
AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCK
Physicochemical Analysis
3887.37 Da
8.22
1.71
1.40
0.0428
-0.21
0.23
0.12
29.25
19.75
0.0750
12490.00
12990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1601.09
-26.47
62.0
62.0
120.0
265.0
7.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206963 VERIFIED: YES
Provenance & Taxonomy
Fagopyrum esculentum [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Clavibacter michiganensis
PMID12951494 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951494/
RECORD: Rec_0221297 VERIFIED: YES
Provenance & Taxonomy
Fagopyrum esculentum [Plant]
Chitin-binding, Hevein, Defensin
3617
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Clavibacter michiganensis subsp. michiganensis
14 μg/mL
IC50
PaperPubMed PMID 15784998 | PubMed PMID 12951490 PMID15784998;12951490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15784998/
RECORD: Rec_0233148 VERIFIED: YES
Provenance & Taxonomy
Fagopyrum esculentum [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Erwinia carotovora
PMID12951494 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951494/
RECORD: Rec_0251478 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0252166 VERIFIED: YES
Provenance & Taxonomy
Fagopyrum esculentum [Plant]
Chitin-binding, Hevein, Defensin
3617
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Erwinia carotovora subsp. carotovora
11 μg/mL
IC50
PaperPubMed PMID 15784998 | PubMed PMID 12951490 PMID15784998;12951490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15784998/
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