Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC85H147N25O22S9

DescriptionStandard

        ICIFCCGCCRKAICGMCCKT
    

Molecular Weight2159.82 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.1339

GRAVY Index1.31

Hydrophobic Moment 0.36

Boman Index0.21

Instability Index9.50

Aliphatic Index 63.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 750.39

LogP -7.63

H-bond Donors 35.0

H-bond Acceptors 34.0

Rotatable Bonds 71.0

Heavy Atoms 141.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295421 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)