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MYP_110198
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Basic Information
Chicken CATH-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
26 amino acids
C148H250N44O31
Standard
Sequence
RVKRVWPLVIRTVIAGYNLYRAIKKK
Physicochemical Analysis
3141.84 Da
11.60
7.75
7.54
0.2982
-0.07
0.78
-0.12
8.01
127.31
0.1154
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1253.28
-6.00
47.0
39.0
105.0
223.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235064 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytolytic
Staphylococcus aureus 25923
0.8 μM
MIC
PaperPubMed PMID: 16326712 | PubMed PMID: 16817888 PMID16326712;16817888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16326712/
RECORD: Rec_0242652 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus MRSA
PMID16326712 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16326712/
RECORD: Rec_0244199 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytolytic
Klebsiella pneumoniae 13883
0.8 μM
MIC
PaperPubMed PMID: 16326712 | PubMed PMID: 16817888 PMID16326712;16817888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16326712/
RECORD: Rec_0246064 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
cathelicidin family
9031; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial cathelicidin family Host defense
PaperPDB 2AMN structural record; NMR; chain A; residues 1-26
RECORD: Rec_0251537 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
1-440 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/18568863/ PMID18568863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18568863/
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