Peptide Database

Peptide NameDefensin Lucifensin (Sericasin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC438H692N126O124S9

DescriptionStandard

        MKFFMVFAVTFCLALSFVSQSLALPADDEAHFVDGLEALKTIEPELHGRYKRATCDLLSGTGVKHSACAAHCLLRGNRGGYCNGRAICVCRN
    

Molecular Weight9995.53 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0194

GRAVY Index0.23

Hydrophobic Moment 0.58

Boman Index0.10

Instability Index32.80

Aliphatic Index 85.98

Aromaticity 0.0870

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3977.33

LogP -39.61

H-bond Donors 147.0

H-bond Acceptors 139.0

Rotatable Bonds 328.0

Heavy Atoms 697.0

Ring Count 14.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006571 VERIFIED: YES

Provenance & Taxonomy

OrganismLucilia sericata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0126196 VERIFIED: YES

Provenance & Taxonomy

OrganismLucilia sericata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans

RECORD: Rec_0131915 VERIFIED: YES

Provenance & Taxonomy

OrganismLucilia sericata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. pneumoniae (Gram-positive)

RECORD: Rec_0148649 VERIFIED: YES

Provenance & Taxonomy

OrganismLucilia sericata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0226200 VERIFIED: YES

Provenance & Taxonomy

OrganismLucilia sericata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. pyogenes (Gram-positive)

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