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MYP_110140
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Basic Information
Innate defence regulator peptide 1002
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
12 amino acids
C79H129N25O14
Standard
Sequence
VQRWLIVWRIRK
Physicochemical Analysis
1653.03 Da
12.00
3.73
3.52
0.3111
-0.12
0.16
-0.20
60.11
145.83
0.1667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
669.81
-1.19
26.0
18.0
54.0
118.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012680 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Immunomodulatory peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Immunomodulatory
Mycobacterium tuberculosis H37Rv
11800 μg/mL
MIC
PMID23555622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23555622/
RECORD: Rec_0160621 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAO1 strain H103
PMID29107983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29107983/
RECORD: Rec_0223874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Klebsiella pneumoniae LM21
6.053 μM
Confocal microscopy-fluorescence
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0271096 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa
1.211 μM
Crystal violet assay
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0292968 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 9017656 B2 Evidence URLhttps://patents.google.com/patent/US9017656B2/en PatentUS 9017656 B2
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