‹ ›
MYP_110129
← PREVIOUS NEXT → BACK
Basic Information
PAMP (Proadrenomedullin N-terminal 20 peptide)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
20 amino acids
C112H177N35O28
Standard
Sequence
ARLDVASEFRKKWNKWALSR
Physicochemical Analysis
2461.82 Da
11.00
3.80
3.60
0.1898
-0.95
0.53
-0.35
39.26
68.50
0.1500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1069.71
-8.52
40.0
32.0
83.0
175.0
5.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0382276 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0389166 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proadrenomedullin N-20 terminal peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation
brain and pituitary gland
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID16315141 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16315141/
RECORD: Rec_0424732 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep red blood cells
256 μM
Hemolysis
PMID32439180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32439180/
FIRST PREV 1 2 3 4
Showing 3 records on this page · Page 4 of 4