Peptide Database

Peptide Name[Ala15 ]Cyclo(Lys21 -Asp 25)GRF(1 -29)-NH2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC153H237N39O42S3

DescriptionStandard

        YADAIFTNSYRVLAQLSARCYCLKLLQCY
    

Molecular Weight3390.95 Da

Isoelectric Point (pI)8.61

Net Charge (pH 7.0)1.73

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0595

GRAVY Index0.37

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index13.31

Aliphatic Index 104.48

Aromaticity 0.1724

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1336.12

LogP -10.29

H-bond Donors 51.0

H-bond Acceptors 47.0

Rotatable Bonds 108.0

Heavy Atoms 237.0

Ring Count 5.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346006 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGHRH/CRF

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsComposite modified token cyclo

Bio-Activity Profile

Function

Endocrine

MethodHPLC

Half-LifePorcine plasma, in vitro; >14400 s