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MYP_110109
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Basic Information
Sushi 1 [K3,5G;M7L;S11L;P14G;G16R;P22F;P23K;C25L;I26N;E28K;S33,34K], SRP-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C174H285N53O40S3
Standard
Sequence
GFGLGGLARILCLGNRQWSNFFKKLNRKCAMVKK
Physicochemical Analysis
3855.65 Da
11.13
7.74
7.50
0.2275
-0.12
0.77
-0.04
15.65
83.24
0.1176
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1547.80
-13.09
57.0
51.0
135.0
270.0
5.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922[MBC90 >50 microM
PMID30279591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279591/
RECORD: Rec_0107264 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
50
6.25 μM
MBC
PMID30279591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279591/
RECORD: Rec_0130971 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID30279591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279591/
RECORD: Rec_0211728 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922[MBC50 >50 microM
PMID30279591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279591/
RECORD: Rec_0219388 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
12.5 μM
MIC
PaperAn engineered arginine-rich alpha-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice
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