MYP_110106
Magainin-2 [G3,18K; K4,10,14Dap; F5W; A15K; E19Dap; M21Nle]
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
23 amino acids
-
contains X representing unresolved or non-standard residue
GIKXWLHSAXKFGXKFVKXIXNS
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0023460
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(4/10/14/19)=Dap; X(21)=Nle
Bio-Activity Profile
Antimicrobial
Anticancer
PANC-1
35.7±0.7 μM
EC50
RECORD: Rec_0104079
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(4/10/14/19)=Dap; X(21)=Nle
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
HEK293
100 μM
EC50
RECORD: Rec_0211191
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(4/10/14/19)=Dap; X(21)=Nle
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
Human kidney-derived GM cells
21
EC50
RECORD: Rec_0321114
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(4/10/14/19)=Dap; X(21)=Nle
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic