Peptide Database

Peptide NameHost defense peptide esculentin-2-RA2

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC377H631N97O114S5

DescriptionStandard

        MLTLKKSLLLLFFLGTISLSFCQEERAADEEDNGEVEEVKRGIFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC
    

Molecular Weight8506.95 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0065

GRAVY Index0.13

Hydrophobic Moment 0.67

Boman Index0.08

Instability Index16.50

Aliphatic Index 105.13

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3426.73

LogP -29.73

H-bond Donors 121.0

H-bond Acceptors 119.0

Rotatable Bonds 303.0

Heavy Atoms 593.0

Ring Count 4.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202466 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana margaretae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence