Peptide Database

Peptide Namenatriuretic peptide TcNP-a

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC152H248N44O54S3

DescriptionStandard

        SGSETAKIGDGCFGLPIDRIGSASGMGCGSVPKPTPGGS
    

Molecular Weight3652.05 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.56

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.12

Hydrophobic Moment 0.47

Boman Index0.15

Instability Index21.68

Aliphatic Index 52.56

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1521.64

LogP -24.05

H-bond Donors 54.0

H-bond Acceptors 57.0

Rotatable Bonds 116.0

Heavy Atoms 253.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018297 VERIFIED: YES

Provenance & Taxonomy

OrganismTropidechis carinatus [Animal]

Familynatriuretic peptide TcNP

Tax ID100989

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0282700 VERIFIED: NO