Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC751H1176N224O217S6

DescriptionStandard

        MARVQFKPRESTDAIFVHCSATKPNQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEEGRDEMAVGSHVKGHNHNSIGVCLVGGIDDKGKFEANFTPAQMQSLRSLLVTLLAKYKGAVLRAHHDVAPKACPSFDLKRWWETNELVTSDRG
    

Molecular Weight17007.13 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.50

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index36.92

Aliphatic Index 75.50

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7114.58

LogP -71.42

H-bond Donors 250.0

H-bond Acceptors 234.0

Rotatable Bonds 568.0

Heavy Atoms 1198.0

Ring Count 29.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221425 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage EG1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic