‹ ›
MYP_110065
← PREVIOUS NEXT → BACK
Basic Information
Wollamide B [V4I,N5S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
WLLISX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0016621 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28423019 PMID28423019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28423019/
RECORD: Rec_0052976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
100 μM
IC50
PMID28423019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28423019/
RECORD: Rec_0065066 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
100 μM
IC50
PaperPubMed PMID: 28423019 PMID28423019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28423019/
RECORD: Rec_0175444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
15 μM
MIC
PMID28423019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28423019/
RECORD: Rec_0247149 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
cyclic peptide [Cyclic]
all-D amino-acid peptide [D]
None
None
Third residue is D-leucine and x= ornithine
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
15 μM
MIC
PMID28423019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28423019/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2