Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC849H1382N246O253S8

DescriptionStandard

        MDTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARDSFDISCDKDNRRFALLGNFFRKAREKIGKEFKRIVQRIKDFLQHLVPRTEA
    

Molecular Weight19340.07 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)3.57

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.42

Hydrophobic Moment 0.94

Boman Index-0.13

Instability Index41.86

Aliphatic Index 87.71

Aromaticity 0.0647

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8120.63

LogP -88.38

H-bond Donors 285.0

H-bond Acceptors 266.0

Rotatable Bonds 652.0

Heavy Atoms 1356.0

Ring Count 23.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036058 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyCathelicidin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0331566 VERIFIED: YES