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MYP_110033
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Basic Information
EcAMP3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
35 amino acids
C172H286N72O57S5
Standard
Sequence
GADRCRERCERRHRGDWQGKQRCLMECRRREQEED
Physicochemical Analysis
4434.88 Da
8.55
1.83
1.50
0.0523
-2.25
0.54
-0.89
103.09
14.00
0.0286
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2207.18
-27.83
85.0
65.0
159.0
306.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194960 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Hairpin-like peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aspergillus niger
22.4 μM
IC50
PaperPubMed PMID 24275143 PMID24275143 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24275143/
RECORD: Rec_0203188 VERIFIED: YES
Provenance & Taxonomy
Echinochloa [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
F. Graminearum
5.5 ± 0.3 μM
MIC
PMID31012001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31012001/
RECORD: Rec_0204072 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 65.7%, E 0.0%, T 17.1%, C 17.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0265315 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crusgalli [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
plant fungal pathogens, including Fusarium graminearum
5.5 μM
IC50
PaperA novel hairpin-like antimicrobial peptide from barnyard grass (Echinochloa crusgalli L.) seeds: Structure-functional and molecular-genetics characterization
RECORD: Rec_0265598 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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