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MYP_110025
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Basic Information
PM III
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C98H153N37O21S4
Standard
Sequence
RRGCFRVCYRGFCFQRCR
Physicochemical Analysis
2313.76 Da
10.66
5.72
5.46
0.3177
-0.56
0.72
-0.50
22.44
16.11
0.2222
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
992.74
-10.20
43.0
31.0
75.0
160.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0114278 VERIFIED: YES
Provenance & Taxonomy
horseshoe crab Limulus polyphemus [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells (hBRC)
46 μM
HC50
PaperPubMed PMID: 30486233 PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0126251 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p
0.25 μM
MIC
PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0143198 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
0.5 μM
MIC
PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0145638 VERIFIED: YES
Provenance & Taxonomy
horseshoe crab Limulus polyphemus [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
SK-BR-3
9.9±0.1 μM
IC50
PaperPubMed PMID: 30486233 PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0170710 VERIFIED: YES
Provenance & Taxonomy
horseshoe crab Limulus polyphemus [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 30486233 PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
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