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MYP_109993
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Basic Information
L12P
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C64H99N23O17S
Standard
Sequence
LCLRNWDQGHRP
Physicochemical Analysis
1494.68 Da
8.26
0.84
0.57
0.0699
-1.29
0.66
-0.35
58.96
65.00
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
666.38
-6.28
24.0
20.0
46.0
105.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0316203 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Candida albicans SA40
PMID28883642;30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28883642/
RECORD: Rec_0325135 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Candida albicans UM4
PMID28883642;30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28883642/
RECORD: Rec_0334985 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 30654366 PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
RECORD: Rec_0342124 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
Coxsackie virus B5 | Vero cells
50 μg/mL
% inhibition
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperAntiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Sala A, Ardizzoni A, Ciociola T, Magliani W, Conti S, Blasi E, Cermelli C | Intervirology. 2018;61(4):166-173. | DOI:10.1159/000494354 | PMID:30654366 PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/
RECORD: Rec_0387594 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Coxsackievirus B5
PMID28883642;30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28883642/
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