Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC514H820N140O152S10

DescriptionStandard

        ISVMKPCLMTISILLILVHKTPGGLFRSYYGKSQEESWNPCQLHQGTCRNACRKYELQYLTCLNHEKCCLKFFVKVATANNVKEESNSNSSLSVTMLSNYSQI
    

Molecular Weight11713.51 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.96

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.0481

GRAVY Index-0.18

Hydrophobic Moment 0.55

Boman Index0.02

Instability Index45.13

Aliphatic Index 84.17

Aromaticity 0.0874

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4750.10

LogP -49.94

H-bond Donors 171.0

H-bond Acceptors 170.0

Rotatable Bonds 393.0

Heavy Atoms 816.0

Ring Count 16.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239017 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence