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MYP_109986
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Basic Information
PR-PG
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C165H271N59O30S4
Standard
Sequence
RFRRLRWKTRWRLKKICYCRRRFCVCV
Physicochemical Analysis
3689.55 Da
11.72
11.72
11.45
0.4339
-0.74
0.53
-0.60
110.96
64.81
0.1852
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1527.12
-9.81
66.0
46.0
124.0
258.0
7.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119509 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 21625
14.8 μg/mL
MIC
PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
RECORD: Rec_0152159 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 29212
7.4 μg/mL
MIC
PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
RECORD: Rec_0181588 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 11060
7.4 μg/mL
MIC
PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
RECORD: Rec_0189757 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 10419
14.8 μg/mL
MIC
PaperCharacterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of α-helix-based peptide amphiphiles. Biomaterials. 2015 Jun;52:517-30. doi: 10.1016/j.biomaterials.2015.02.063. PMID: 25818457. PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
RECORD: Rec_0197273 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
hRBC
294.3 μg/mL
Hemolysis
PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
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