Peptide Database

Peptide NameNL8

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC36H50N12O15

DescriptionStandard

        HTDNGSNF
    

Molecular Weight890.85 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.1439

GRAVY Index-1.60

Hydrophobic Moment 0.31

Boman Index-0.18

Instability Index-38.25

Aliphatic Index 0.00

Aromaticity 0.1250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 459.64

LogP -7.77

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 27.0

Heavy Atoms 63.0

Ring Count 2.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270455 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:Inhibition of 3′-processing catalyzed by integrase

Activity2000 μM

MethodIC50

RECORD: Rec_0385336 VERIFIED: YES