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MYP_109976
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Basic Information
Turgencin B Mox2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
35 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIKEXLCNXACAQTVCKKSGGPLCDTCQAACKALG
Physicochemical Analysis
0.00 Da
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026379 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=MET-OXD
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
50 μM
IC50
PaperPubMed PMID: 31940927 PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0142676 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
100 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0151322 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 9144
100 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0179144 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Antimicrobial Antibacterial
Human melanoma A2058
50.0 μM
IC50
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0211401 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>50.0 μM
IC50
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
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