Peptide Database

Peptide Nameprogrammed cell death 1 ligand 1

Function Ontology

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length290 amino acids

Chemical FormulaC1489H2363N401O436S13

DescriptionStandard

        MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
    

Molecular Weight33274.96 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.73

Net Charge (pH 7.4) -1.58

Charge Density (pH 7.0) -0.0025

GRAVY Index-0.23

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index34.85

Aliphatic Index 94.41

Aromaticity 0.0862

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33265.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416556 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsDisulphide bonds: cys40-cys114, cys155-cys209 N-linked glycosylation at residues 35, 192, 200 and 219

Bio-Activity Profile

Function

Signaling peptide

Targetprogrammed cell death 1 (CD279) (Human)