Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC705H1181N205O215S4

DescriptionStandard

        VPIRKVQDDTKTLIKTIVTRINDISHTQAVSSKQRVAGLDFIPGLHPVLSLSRMDQTLAIYQQILTSLHSRNVVQISNDLENLRDLLHLLASSKSCPLPRARGLESFESLGGVLEASLYSTEVVALSRLQAALQDMLRRLDLSPGC
    

Molecular Weight16097.42 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)2.08

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.0142

GRAVY Index0.02

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index44.22

Aliphatic Index 118.84

Aromaticity 0.0274

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6784.38

LogP -71.96

H-bond Donors 239.0

H-bond Acceptors 225.0

Rotatable Bonds 545.0

Heavy Atoms 1129.0

Ring Count 14.0

Amide Bonds 158.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0140087 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus thibetanus [Animal]

FamilyLeptin

Tax ID9642

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic