Peptide Database

Peptide NameSLAY-screened peptide P3610

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC92H143N39O31

DescriptionStandard

        RHHHTSAHDISDGRRSHGID
    

Molecular Weight2291.36 Da

Isoelectric Point (pI)7.16

Net Charge (pH 7.0)0.20

Net Charge (pH 7.4) -0.26

Charge Density (pH 7.0) 0.0101

GRAVY Index-1.66

Hydrophobic Moment 0.42

Boman Index-0.43

Instability Index52.30

Aliphatic Index 44.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1138.14

LogP -16.61

H-bond Donors 42.0

H-bond Acceptors 36.0

Rotatable Bonds 75.0

Heavy Atoms 162.0

Ring Count 5.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417633 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/