Peptide Database

Peptide NamePN-CATH1

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC178H296N58O42S2

DescriptionStandard

        KKCNFFCKLKKKVKSVGSRNLIGSATHHHRIYRV
    

Molecular Weight3984.75 Da

Isoelectric Point (pI)10.78

Net Charge (pH 7.0)9.99

Net Charge (pH 7.4) 9.60

Charge Density (pH 7.0) 0.2939

GRAVY Index-0.62

Hydrophobic Moment 0.59

Boman Index-0.25

Instability Index-1.23

Aliphatic Index 74.41

Aromaticity 0.0882

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1664.83

LogP -16.18

H-bond Donors 63.0

H-bond Acceptors 57.0

Rotatable Bonds 140.0

Heavy Atoms 280.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422773 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans CMCC 98001

Activity100 μg/mL

MethodMIC

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