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MYP_109907
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Basic Information
PN-CATH1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C178H296N58O42S2
Standard
Sequence
KKCNFFCKLKKKVKSVGSRNLIGSATHHHRIYRV
Physicochemical Analysis
3984.75 Da
10.78
9.99
9.60
0.2939
-0.62
0.59
-0.25
-1.23
74.41
0.0882
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1664.83
-16.18
63.0
57.0
140.0
280.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319230 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa CMCC 10104
18.75 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0323292 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae
9.38 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0331439 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant
inactive: Bacillus cereus CMCC63301, Enterococcus faecalis ATCC 29212, Staphylococcus epidermidis, E.faecium
>100 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
RECORD: Rec_0333308 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Shigella flexneri ATCC 12022
18.75 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0334857 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
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