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MYP_109907
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Basic Information
PN-CATH1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C178H296N58O42S2
Standard
Sequence
KKCNFFCKLKKKVKSVGSRNLIGSATHHHRIYRV
Physicochemical Analysis
3984.75 Da
10.78
9.99
9.60
0.2939
-0.62
0.59
-0.25
-1.23
74.41
0.0882
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1664.83
-16.18
63.0
57.0
140.0
280.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275197 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0282994 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant
Candida albicans and C.glabrata
>100 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
RECORD: Rec_0286803 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0294943 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant
Escherichia coli CMCC44102, Aeromonas sobria
9.4 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
RECORD: Rec_0312569 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant
active: Staphylococcus aureus CMCC26003, C. perfringens ATCC 13124
4.7 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
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