Peptide Database

Peptide NamePutative beta-defensin 109B (Defensin; beta 109; pseudogene 1B) (Defensin; beta 109B)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC445H730N122O111S10

DescriptionStandard

        MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCCRAWWILMPIPTPLIMSDYQEPLKPNLK
    

Molecular Weight9885.96 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0416

GRAVY Index0.44

Hydrophobic Moment 0.47

Boman Index0.16

Instability Index62.70

Aliphatic Index 124.37

Aromaticity 0.0575

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3665.32

LogP -22.24

H-bond Donors 132.0

H-bond Acceptors 127.0

Rotatable Bonds 322.0

Heavy Atoms 688.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401191 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic