Peptide Database

Peptide NameNL4

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC33H49N9O10

DescriptionStandard

        VHVASGY
    

Molecular Weight731.80 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.18

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0257

GRAVY Index0.64

Hydrophobic Moment 0.19

Boman Index0.42

Instability Index-3.56

Aliphatic Index 97.14

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 307.06

LogP -2.82

H-bond Donors 11.0

H-bond Acceptors 11.0

Rotatable Bonds 20.0

Heavy Atoms 52.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0278988 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetinhibition of strand transfer catalyzed by integrase

Activity2000 μM

MethodIC50

RECORD: Rec_0396384 VERIFIED: YES