Peptide Database

Peptide NameBmK AGP-SYPU2

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC317H475N95O97S9

DescriptionStandard

        VKDGYIADDRNCPYFCGRNAYCDGECKKNRAESGYCQWASKYGNACWCYKLPDDARIMKPGRCNGG
    

Molecular Weight7457.33 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)2.66

Net Charge (pH 7.4) 2.30

Charge Density (pH 7.0) 0.0402

GRAVY Index-0.93

Hydrophobic Moment 0.46

Boman Index-0.20

Instability Index25.18

Aliphatic Index 31.21

Aromaticity 0.1364

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3144.43

LogP -35.74

H-bond Donors 117.0

H-bond Acceptors 109.0

Rotatable Bonds 241.0

Heavy Atoms 518.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280750 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense